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KMID : 1144220180240010029
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Journal of Menopausal Medicine
2018 Volume.24 No. 1 p.29 ~ p.33
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The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial
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Afiat Maliheh
Amini Elham
Ghazanfarpour Masumeh
Nouri Bahareh
Mousavi Mahsa Sadat
Babakhanian Masoudeh
Rakhshandeh Hassan
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Abstract
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Objectives: The present trial aimed to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles.
Methods: In this double blind, randomized and placebo-controlled trial, sixty eligible postmenopausal women were randomly assigned into the fennel and placebo groups. Total blood cholesterol, cholesterol fractions, and triglycerides were tested at the baseline, and after three-month follow-up.
Results: There was no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol (LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups. In addition, in both groups, a paired t.test showed no significant difference in all mentioned parameters, except for HDL-C, indicating significant borderline improvement (P = 0.052) in the fennel group.
Conclusions: The fennel group revealed a very slight positive change in LDL-C, triglyceride and HDL-C. Further studies with longer durations, higher doses, and larger sample sizes are recommended to validate the results.
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KEYWORD
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Foeniculum, Lipids, Postmenopause
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